Clinical Trials

Clinical trials, also called clinical studies, test new methods to treat, diagnose and prevent cancer. Only treatments that provide promising results in laboratory tests advance to clinical trials.

Phase I trials are the first step at testing new treatments in people. They help researchers determine the best way to administer a new treatment and the appropriate dosage. These trials also establish whether a treatment has any potentially harmful side effects. Phase 1 trials involve a small number of people.

Phase II trials focus on learning whether a new treatment can shrink a tumor, improve blood test results or provide other desirable effects. There are usually involving fewer than 100 participants.

Phase III trials compare the new treatment to the best existing treatment for a particular type of cancer. Many patients — from the hundreds to even the thousands — receive either the new treatment or the best existing treatment. A Phase III trial may involve adding a new drug to an already-proven combination of drugs to see if the new combination is more effective.

For a more complete description of how clinical trials are structured, see our paper Participating in a Prostate Cancer Clinical Trial.

To Learn More About Clinical Trials

The National Cancer Institute provides a Clinical Studies Support Center in Bethesda, Maryland. You can talk with an Information Specialist by calling 1-888-NCI-1937 between 9:00am and 5:00pm Eastern Time, Monday – Friday. You may also contact the PCRI Helpline.

Clinical Trials Dictionary

To Locate Clinical Trials

In the window below (entitled, “Prostate Cancer Trials”) is a web portal which is sponsored by “The Clinical Trial Forum Network.” This portal lists prostate cancer-related clinical trials in the Los Angeles area that are being conducted by the five most prominent regional research institutions, namely:

  • Prostate Oncology Specialists
  • USC Norris Comprehensive Cancer Center
  • City of Hope National Medical Center
  • UCLA Jonsson Comprehensive Cancer Center
  • Cedars-Sinai Medical Center

If you are accessing our website from a cellphone or other small-format device, we recommend that you click the “Mobile Phone Version” button (below left), which will resize the content to your particular screen size.

NOTE: If you have an older browser and cannot clearly see the content in the window below, click here for an older version of our clinical trials report. (It will open in a new browser window)