Comparing Treatments

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How Do Prostate Cancer Treatments Compare?

There have been no randomized trials comparing the various treatments for prostate cancer. If there is a high probability of Organ Confined Disease, and assuming that general health is very good, local therapy can be considered in hopes of curing the disease.

Men who are in the Low-Risk Category can forgo immediate treatment and simply monitor their situation in a program called Active Surveillance. This consists of regular PSA testing, prostate exams and periodic repeat biopsies.

Men with Intermediate-Risk disease usually start with one kind of treatment, local or systemic. Men with High-Risk prostate cancer generally get two or more kinds of treatment. For instance, the doctor might use testosterone deprivation and radiation.

Regardless of treatment selection, Finding an Expert raises the probability of a good result.

Lower urinary tract symptoms (LUTS) with AUA score of 10 or higher increases morbidity following seeds, EBRT, IMRT, HDR and Cryo. Gland volume of greater than 40 cc may increase risk of urinary symptoms post-radiation therapy (any kind of RT) as well as same problem with cryosurgery.
See the discussion of BPH under Prostate Basics

You can develop a basis for comparing treatments by reviewing the resources below:


PCRI Resources:

You will also find detail articles on each treatment on the PCRI Papers webpage.


Related Resources:

These articles provide patient evaluations of the impact on quality of life by radical prostatectomy, external radiation and brachytherapy.